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Good news keeps coming! The enzyme product 3′-sialic acid lactose sodium salt has completed the registration as a new cosmetic ingredient.

Recently, Enzyme Products successfully completed the cosmetic new ingredient registration for “3′-Sialoyllactose Sodium Salt” (3′-SL) (National Cosmetic Ingredient Registration No. 20250005) . 3′-SL is the third innovative ingredient registered after acetylcarnosine and collagen tripeptide , and it is also Enzyme Products’ first human milk oligosaccharide (HMOs) product to complete cosmetic new ingredient registration. The company adheres to independent innovation in ingredient creation, continuously enriching its product line to bring consumers more high-quality, high-efficiency skincare options.

Registration information for finished enzyme product 3′-sialic acid lactose sodium salt

Enzyme product 3′-Sialyllactose sodium salt

3′-Sialyllactose sodium salt (3′-SL) is a natural functional trisaccharide formed by the combination of sialic acid and lactose via an α-2,3 glycosidic bond, and is widely found in breast milk. In the field of functional skincare, this ingredient exhibits significant moisturizing, repairing, anti-inflammatory, and soothing effects, meeting diverse skincare needs.

Enzyme product information: 3′-Sialolactose sodium salt

Core benefits:

1. Moisturizing and Barrier Repair: 3′-SL can promote the expression of the aquaporin 3 (AQP3) gene, enhance the skin’s stratum corneum’s ability to retain water, and promote the repair of damaged barriers.  

3′-SL Human Efficacy Experimental Data

2. Anti-inflammatory and soothing:For sensitive skin or skin easily irritated by external stimuli, 3′-SL has good anti-inflammatory properties, which can inhibit the expression of inflammatory factors IL-6 and TNF-α, and relieve skin redness and other problems.

3′-SL Human Efficacy Experimental Data

3. Promote microecological balance:As a prebiotic, 3′-SL helps maintain a healthy skin microbiome and improve skin discomfort symptoms.

3′- SL is naturally derived, gentle, non-irritating, and has low allergenicity , meeting consumers’ demand for safe skincare products. It is especially suitable for sensitive skin, infant skin, and problem skin . 3′-SL can be used in various product types, including serums, creams, sprays, and masks. Its excellent compatibility allows it to be adapted to multiple formulation systems, bringing .

Traditional methods for extracting sialic acid-lactose raw materials rely primarily on limited natural resources, such as milk. This approach is not only costly and inefficient but also has a significant impact on the environment. The resulting enzyme product utilizes biosynthesis technology, combining microbial fermentation and enzyme engineering to achieve large-scale production of 3′-SL enzymes. The production process is green, environmentally friendly, and low-polluting, aligning with sustainable development trends. The resulting product boasts high purity and consistency, making it safer and more effective for applications in functional skincare and nutritional health .

Regarding enzyme products

Enzyme Products is committed to becoming a global leader in green active ingredients . Utilizing next-generation synthetic biology technology, Enzyme Products focuses on the green production of bioactive ingredients such as peptides, proteins, sugars, nucleic acids, and lipids. Leveraging over 20 years of research and industry experience accumulated by its founding team, the company has established a leading multidisciplinary technology platform in China. It has achieved large-scale production of dozens of green active ingredients, including Smegglutinin, S -propoxygenin, ergothionein, ectoin, collagen tripeptide, human milk oligosaccharides, ceramides, NAD+, NMN, copper peptide, carnosine, and glutathione. It has cumulatively provided high-quality green active ingredients to over 2,000 well-known companies in the fields of functional skincare, biomedicine, nutrition and health, and animal nutrition . The company ranks among the top international companies in terms of R&D investment, scale, and output value. It has undertaken a number of key provincial and municipal R&D projects, applied for nearly 200 invention patents, and received more than ten national and local titles, including National Specialized, Refined, and Innovative Small and Medium-sized Enterprise, National High-tech Enterprise, Guangdong Provincial Postdoctoral Innovation Practice Base, Shenzhen Peacock Team, Shenzhen Potential Unicorn Enterprise, Zhuhai Innovation and Entrepreneurship Team, and Gansu Provincial Specialized, Refined, and Innovative Small and Medium-sized Enterprise. It has also been recognized as one of the Top 20 High-Growth Enterprises in Shenzhen in 2024, the Harvard Business Review High-Energy Innovation Team Award in 2023, and one of the Top 100 High-Growth Enterprises in Shenzhen in 2022.

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